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DRUGS / ANIMALS: The role of transgenic livestock in the treatmentof human disease

------------------------------- GENET-news -------------------------------
TITLE:  CAST paper examines the role of transgenic livestock in the
        treatment of human disease
SOURCE: The Council for Agricultural Science and Technology, USA
AUTHOR: Press Release
DATE:   14.05.2007

CAST paper examines the role of transgenic livestock in the treatment of
human disease

May 14, 2007...Washington, D.C. The Council for Agricultural Science and
Technology (CAST) is releasing a new Issue Paper, The Role of Transgenic
Livestock in the Treatment of Human Disease. Written and reviewed by a
six-member task force, this paper is Part 6 in the CAST series on
"Animal Agriculture's Future through Biotechnology."

Transgenic livestock have the potential to play a critical role in the
production of new medications for the treatment of human disease.
According to Task Force Chair Carol L. Keefer, University of Maryland,
"This role may consist of the actual production of recombinant proteins,
including biotherapeutic proteins and antibodies, or it may involve the
development of new animal models that can be used in studies relating to
human diseases. Both approaches can provide significant advances in the
development of new treatments."  

Specific topics covered in the paper include:
- Methods of transgenic animal production, including pronuclear
microinjection and somatic cell nuclear transfer (SCNT)
- Recent developments in SCNT-based gene transfer technologies,
including gene targeting and transchromosomic technology
- Transgenic animals as disease models for the development of new treatments
- Transgenic livestock as producers of new medications, including
biopharming, bioproducts from milk, and bioproducts from serum
- Economic and regulatory issues
- Societal issues
- An in-depth description of the steps involved in producing transgenic
animals by SCNT (Appendix 1.)

"As scientists continue to perfect technologies in the near future, more
applications of transgenic animals for the treatment of human diseases
will become available," concludes CAST Executive Vice President John
Bonner. "The new CAST Issue Paper suggests that education regarding the
advantages and challenges associated with this new technology is the key
to public understanding, and CAST is pleased to be part of that effort
by providing this important contribution to the scientific literature."

The full text of the paper The Role of Transgenic Livestock in the
Treatment of Human Disease (Issue Paper No. 35) may be accessed on the
CAST website at, along with many of CAST's other
scientific publications, and is available in hardcopy for $5.00
(includes shipping) by contacting the CAST office at 515-292-2125. CAST
is an international consortium of 37 scientific and professional
societies. It assembles, interprets, and communicates credible science-
based information regionally, nationally, and internationally to
legislators, regulators, policymakers, the media, the private sector,
and the public.

Dr. Carol L. Keefer: Phone: 301-405-3933; E-mail:
Dr. John M. Bonner: Phone: 515-292-2125, ext. 25; E-mail: jbonner@cast-

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